Dendritic Cells in Hematopoietic Stem Cell Transplantation
نویسندگان
چکیده
Dendritic cells (DC) are highly specialized antigen-presenting cells (APC) that are pivotal in regulating the balance between immune tolerance and protective immunity. This functional versatility is highlighted in the context of allogeneic hematopoietic stem cell transplantation (allo-HSCT), where DC are crucial for the induction and modulation of graft-versus-host reactions. Furthermore, in the process of immune restoration after allo-HSCT, DC play a central role in generating protective immunity against pathogens. The importance of DC in directing the immune system during the complex immunological situation after allo-HSCT warrants further research, aimed at uncovering the therapeutic potential they hold in this setting.
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